MEDICAMENTOUS ABORTION WITH MIFEPRISTONE AND MISOPROSTOL IN SERBIA AND MONTENEGRO


Depletion of lamins B1 and B2 promotes chromatin mobility and induces differential gene expression by a mesoscale-motion-dependent mechanism

Abstract Background B-type lamins are critical nuclear envelope proteins that interact with the three-dimensional genomic architecture.However, identifying the direct roles of B-lamins on dynamic genome organization has been challenging as their joint depletion severely impacts Glass cell viability.To overcome this, we engineered mammalian cells to

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Cardiac mortality predictability of T-wave alternans in young ST-elevated myocardial infarction patients with preserved cardiac function

Objective: Primary prevention of sudden cardiac death in ST-elevation myocardial infarction (STEMI) is a complicated issue due to the highly heterogeneous population.The effect of T-wave alternans (TWA) on cardiac mortality has been examined in various populations, most often in patients with a high risk of fatal arrhythmia, such as patients with a

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Embryonic Stem Cell-Derived Cardiomyocyte Heterogeneity and the Isolation of Immature and Committed Cells for Cardiac Remodeling and Regeneration

Pluripotent stem cells represent one promising source for cell replacement therapy in heart, but differentiating embryonic stem cell-derived cardiomyocytes (ESC-CMs) are highly heterogeneous and show a variety of maturation states.In this study, we employed an ESC clonal line that contains a cardiac-restricted ncx1 promoter-driven puromycin resista

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